Publications

Job Posting TitleLocationDepartmentDate
Deficiency of angiotensin type 2 receptor rescues obesity but not hypertension induced by overexpression of angiotensinogen in adipose tissue.Yvan-Charvet L, Massiéra F, Lamandé N, Ailhaud G, Teboul M, Moustaid-Moussa N, Gasc JM, Quignard-Boulangé A.Endocrinology. 20092008/10/256 years ago
Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance.Yvan-Charvet L, Even P, Bloch-Faure M, Guerre-Millo M, Moustaid-Moussa N, Ferre P, Quignard-Boulange A.Diabetes. 20052005/03/296 years ago
Gender-related response of lipid metabolism to dietary fatty acids in the hamster.Morise A, Mourot J, Boué C, Combe N, Amsler G, Gripois D, Quignard-Boulangé A, Yvan-Charvet L, Fénart E, Weill P, Hermier D.Br J Nutr. 20062006/03/316 years ago
Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes.Lagathu C, Yvan-Charvet L, Bastard JP, Maachi M, Quignard-Boulangé A, Capeau J, Caron M.Diabetologia. 20062006/07/266 years ago
Prevention of adipose tissue depletion during food deprivation in angiotensin type 2 receptor-deficient mice.Yvan-Charvet L, Even P, Lamandé N, Ferré P, Quignard-Boulangé A.Endocrinology. 20062006/08/056 years ago
Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow.Ranalletta M, Wang N, Han S, Yvan-Charvet L, Welch C, Tall AR.Arterioscler Thromb Vasc Biol. 20062006/08/196 years ago
The failure of torcetrapib: was it the molecule or the mechanism?Tall AR, Yvan-Charvet L, Wang N.Arterioscler Thromb Vasc Biol. 20072007/01/196 years ago
In vivo evidence for a role of adipose tissue SR-BI in the nutritional and hormonal regulation of adiposity and cholesterol homeostasis.Yvan-Charvet L, Bobard A, Bossard P, Massiéra F, Rousset X, Ailhaud G, Teboul M, Ferré P, Dagher G, Quignard-Boulangé A.Arterioscler Thromb Vasc Biol. 20072007/03/176 years ago
Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells.Cui D, Thorp E, Li Y, Wang N, Yvan-Charvet L, Tall AR, Tabas I.J Leukoc Biol. 20072007/06/206 years ago
High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1.Terasaka N, Wang N, Yvan-Charvet L, Tall AR.Proc Natl Acad Sci U S A. 20072007/09/126 years ago
SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL.Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR.J Lipid Res. 20082007/10/266 years ago
[Raising HDL-cholesterol: the future drug therapy for atherosclerosis?].Masson D, Yvan-Charvet L.Med Sci (Paris). 20082008/04/156 years ago
Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions.Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR.Circulation. 20082008/10/156 years ago
Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses.Yvan-Charvet L, Wang N, Tall AR.Arterioscler Thromb Vasc Biol. 20102009/10/036 years ago
Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib.Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR.Arterioscler Thromb Vasc Biol. 20102010/05/086 years ago
Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity.Yvan-Charvet L, Quignard-Boulangé A.Kidney Int. 20112010/10/156 years ago
Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation.Kuo CL, Murphy AJ, Sayers S, Li R, Yvan-Charvet L, Davis JZ, Krishnamurthy J, Liu Y, Puig O, Sharpless NE, Tall AR, Welch CL.Arterioscler Thromb Vasc Biol. 20112011/08/276 years ago
ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice.Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, Wang M, Sanson M, Abramowicz S, Welch C, Bochem AE, Kuivenhoven JA, Yvan-Charvet L, Tall AR.J Clin Invest. 20112011/10/056 years ago
Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport.Rosenson RS, Brewer HB Jr, Davidson WS, Fayad ZA, Fuster V, Goldstein J, Hellerstein M, Jiang XC, Phillips MC, Rader DJ, Remaley AT, Rothblat GH, Tall AR, Yvan-Charvet L.Circulation. 20122012/04/186 years ago
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice.Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR.Circ Res. 20132013/04/116 years ago
Liver X receptor α-dependent iron handling in M2 macrophages: The missing link between cholesterol and intraplaque hemorrhage?Hasty AH, Yvan-Charvet L.Circ Res. 20132013/11/106 years ago
ATP-binding cassette transporters, atherosclerosis, and inflammation.Westerterp M, Bochem AE, Yvan-Charvet L, Murphy AJ, Wang N, Tall AR.Circ Res. 20142014/01/056 years ago
Understanding macrophage diversity at the ontogenic and transcriptomic levels.Gautier EL, Yvan-Charvet L.Immunol Rev. 20142014/10/176 years ago
Cholesterol, inflammation and innate immunity.Tall AR, Yvan-Charvet L.Nat Rev Immunol. 20152015/01/246 years ago
Insulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes.Tondu AL, Robichon C, Yvan-Charvet L, Donne N, Le Liepvre X, Hajduch E, Ferré P, Dugail I, Dagher G.J Biol Chem. 20052005/07/226 years ago
ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis.Yvan-Charvet L, Pagler TA, Seimon TA, Thorp E, Welch CL, Witztum JL, Tabas I, Tall AR.Circ Res. 20102010/05/016 years ago
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis.Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N.Nat Med. 20132013/04/166 years ago
HIF-2α in Resting Macrophages Tempers Mitochondrial Reactive Oxygen Species To Selectively Repress MARCO-Dependent Phagocytosis.Dehn S, DeBerge M, Yeap XY, Yvan-Charvet L, Fang D, Eltzschig HK, Miller SD, Thorp EB.J Immunol. 20162016/09/286 years ago
Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice.Sarrazy V, Viaud M, Westerterp M, Ivanov S, Giorgetti-Peraldi S, Guinamard R, Gautier EL, Thorp EB, De Vivo DC, Yvan-Charvet L.Circ Res. 20162016/03/026 years ago
Is defective cholesterol efflux an integral inflammatory component in myelopoiesis-driven cardiovascular diseases?Yvan-Charvet L, Swirski FK.Eur Heart J. 20182018/05/186 years ago
The modern interleukin-1 superfamily: Divergent roles in obesity.Lee MK, Yvan-Charvet L, Masters SL, Murphy AJ.Semin Immunol. 20162016/10/126 years ago
Poststatin era in atherosclerosis management: lessons from epidemiologic and genetic studies.Yvan-Charvet L, Cariou B.Curr Opin Lipidol. 20182018/03/206 years ago
Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL.Yvan-Charvet L, Matsuura F, Wang N, Bamberger MJ, Nguyen T, Rinninger F, Jiang XC, Shear CL, Tall AR.Arterioscler Thromb Vasc Biol. 20072007/02/276 years ago
Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice.Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C, Tall AR.J Clin Invest. 20072007/11/106 years ago
ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain.Wang N, Yvan-Charvet L, Lütjohann D, Mulder M, Vanmierlo T, Kim TW, Tall AR.FASEB J. 20082007/11/286 years ago
HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis.Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N.Cell Metab. 20082008/05/086 years ago
ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet.Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR.J Clin Invest. 20082008/10/186 years ago
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation.Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR.Science. 20102010/05/226 years ago
ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase.Terasaka N, Westerterp M, Koetsveld J, Fernández-Hernando C, Yvan-Charvet L, Wang N, Sessa WC, Tall AR.Arterioscler Thromb Vasc Biol. 20102010/08/286 years ago
[HDL and its transporters ABCA1 and ABCG1 regulate innate immunity and hematopoietic stem cell proliferation].Gautier EL, Yvan-Charvet L.Med Sci (Paris). 20112011/02/096 years ago
Anti-atherogenic mechanisms of high density lipoprotein: effects on myeloid cells.Murphy AJ, Westerterp M, Yvan-Charvet L, Tall AR.Biochim Biophys Acta. 20122011/08/266 years ago
Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways.Westerterp M, Gourion-Arsiquaud S, Murphy AJ, Shih A, Cremers S, Levine RL, Tall AR, Yvan-Charvet L.Cell Stem Cell. 20122012/08/076 years ago
Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis.Tall AR, Yvan-Charvet L, Westerterp M, Murphy AJ.Arterioscler Thromb Vasc Biol. 20122012/10/196 years ago
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.Gautier EL, Westerterp M, Bhagwat N, Cremers S, Shih A, Abdel-Wahab O, Lütjohann D, Randolph GJ, Levine RL, Tall AR, Yvan-Charvet L.J Exp Med. 20132013/01/166 years ago
Mild renal dysfunction and metabolites tied to low HDL cholesterol are associated with monocytosis and atherosclerosis.Ganda A, Magnusson M, Yvan-Charvet L, Hedblad B, Engström G, Ai D, Wang TJ, Gerszten RE, Melander O, Tall AR.Circulation. 20132013/02/056 years ago
Deficiency of ATP-binding cassette transporter B6 in megakaryocyte progenitors accelerates atherosclerosis in mice.Murphy AJ, Sarrazy V, Wang N, Bijl N, Abramowicz S, Westerterp M, Welch CB, Schuetz JD, Yvan-Charvet L.Arterioscler Thromb Vasc Biol. 20142014/02/086 years ago
Adipose modulation of ABCG1 uncovers an intimate link between sphingomyelin and triglyceride storage.Murphy AJ, Yvan-Charvet L.Diabetes. 20152015/02/266 years ago
Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation.Sarrazy V, Sore S, Viaud M, Rignol G, Westerterp M, Ceppo F, Tanti JF, Guinamard R, Gautier EL, Yvan-Charvet L.Cell Rep. 20152015/09/296 years ago
Can LDL cholesterol be too low? Possible risks of extremely low levels.Olsson AG, Angelin B, Assmann G, Binder CJ, Björkhem I, Cedazo-Minguez A, Cohen J, von Eckardstein A, Farinaro E, Müller-Wieland D, Parhofer KG, Parini P, Rosenson RS, Starup-Linde J, Tikkanen MJ, Yvan-Charvet L.J Intern Med. 20172017/03/166 years ago
Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD.Ganda A, Yvan-Charvet L, Zhang Y, Lai EJ, Regunathan-Shenk R, Hussain FN, Avasare R, Chakraborty B, Febus AJ, Vernocchi L, Lantigua R, Wang Y, Shi X, Hsieh J, Murphy AJ, Wang N, Bijl N, Gordon KM, de Miguel MH, Singer JR, Hogan J, Cremers S, et al.J Mol Cell Cardiol. 20172017/05/106 years ago
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity.Westerterp M, Gautier EL, Ganda A, Molusky MM, Wang W, Fotakis P, Wang N, Randolph GJ, D'Agati VD, Yvan-Charvet L, Tall AR.Cell Metab. 20172017/05/106 years ago
Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production.Viaud M, Ivanov S, Vujic N, Duta-Mare M, Aira LE, Barouillet T, Garcia E, Orange F, Dugail I, Hainault I, Stehlik C, Marchetti S, Boyer L, Guinamard R, Foufelle F, Bochem A, Hovingh KG, Thorp EB, Gautier EL, Kratky D, Dasilva-Jardine P, Yvan-Charvet L.Circ Res. 20182018/03/116 years ago
Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype.Ohanna M, Cerezo M, Nottet N, Bille K, Didier R, Beranger G, Mograbi B, Rocchi S, Yvan-Charvet L, Ballotti R, Bertolotto C.Genes Dev. 20182018/03/246 years ago
Immunometabolism of Phagocytes and Relationships to Cardiac Repair.Zhang S, Bories G, Lantz C, Emmons R, Becker A, Liu E, Abecassis MM, Yvan-Charvet L, Thorp EB.Front Cardiovasc Med. 20192019/04/306 years ago
Macrophage Origin, Metabolic Reprogramming and IL-1 Signaling: Promises and Pitfalls in Lung Cancer.Guilbaud E, Gautier EL, Yvan-Charvet L.Cancers (Basel). 20192019/03/066 years ago
Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair.Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Yvan-Charvet L, Chandel NS, Schumacker PT, Thorp EB.Cell Metab. 20192019/01/016 years ago
Cholesterol Mass Efflux Capacity, Incident Cardiovascular Disease, and Progression of Carotid Plaque.Shea S, Stein JH, Jorgensen NW, McClelland RL, Tascau L, Shrager S, Heinecke JW, Yvan-Charvet L, Tall AR.Arterioscler Thromb Vasc Biol. 20192018/12/266 years ago
Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance.Gilleron J, Bouget G, Ivanov S, Meziat C, Ceppo F, Vergoni B, Djedaini M, Soprani A, Dumas K, Jacquel A, Yvan-Charvet L, Venteclef N, Tanti JF, Cormont M.Cell Rep. 20182018/12/206 years ago
Immunometabolic function of cholesterol in cardiovascular disease and beyond.Yvan-Charvet L, Bonacina F, Guinamard RR, Norata GDCardiovasc Res. 20192019/07/016 years ago
Mesothelial cell CSF1 sustains peritoneal macrophage proliferation.Ivanov S, Gallerand A, Gros M, Stunault MI, Merlin J, Vaillant N, Yvan-Charvet L, Guinamard RR.Eur J Immunol. 20192019/116 years ago
Granulopoiesis and Neutrophil Homeostasis: A Metabolic, Daily Balancing Act.Yvan-Charvet L, Ng LG.Trends Immunol. 20192019/076 years ago
[Does sleep preserve blood vessels?].Yvan-Charvet L, Merlin J.Med Sci (Paris). 20192019/10/186 years ago
REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet.Dumas K, Ayachi C, Gilleron J, Lacas-Gervais S, Pastor F, Favier FB, Peraldi P, Vaillant N, Yvan-Charvet L, Bonnafous S, Patouraux S, Anty R, Tran A, Gual P, Cormont M, Tanti JF, Giorgetti-Peraldi S.FASEB J. 20202020/046 years ago
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms.Viaud M, Abdel-Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, Merlin J, Ayrault M, Guilbaud E, Jacquel A, Auberger P, Wang N, Levine RL, Tall AR, Yvan-Charvet L.Cell Rep. 20202020/03/106 years ago
Interplay between Clonal Hematopoiesis of Indeterminate Potential and Metabolism.Lee MKS, Dragoljevic D, Bertuzzo Veiga C, Wang N, Yvan-Charvet L, Murphy AJ.Trends Endocrinol Metab. 20202020/076 years ago
Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis.Tran S, Baba I, Poupel L, Dussaud S, Moreau M, Gélineau A, Marcelin G, Magréau-Davy E, Ouhachi M, Lesnik P, Boissonnas A, Le Goff W, Clausen BE, Yvan-Charvet L, Sennlaub F, Huby T, Gautier EL.Immunity. 20202020/09/156 years ago
Liver X receptors are required for thymic resilience and T cell output.Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK.J Exp Med. 20202020/10/056 years ago
Metabolic Inflammation in Obesity-At the Crossroads between Fatty Acid and Cholesterol Metabolism.Curley S, Gall J, Byrne R, Yvan-Charvet L, McGillicuddy FC.Mol Nutr Food Res. 20202021/016 years ago
Metabolic Reprogramming of Macrophages in Atherosclerosis: Is It All about Cholesterol?Yvan-Charvet L, Ivanov S.J Lipid Atheroscler. 20202020/056 years ago
The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back AgainHofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, et al.Cancers (Basel). 20192019/02/249 years ago