Deficiency of angiotensin type 2 receptor rescues obesity but not hypertension induced by overexpression of angiotensinogen in adipose tissue. | Yvan-Charvet L, Massiéra F, Lamandé N, Ailhaud G, Teboul M, Moustaid-Moussa N, Gasc JM, Quignard-Boulangé A. | Endocrinology. 2009 | 2008/10/254 years ago |
Deletion of the angiotensin type 2 receptor (AT2R) reduces adipose cell size and protects from diet-induced obesity and insulin resistance. | Yvan-Charvet L, Even P, Bloch-Faure M, Guerre-Millo M, Moustaid-Moussa N, Ferre P, Quignard-Boulange A. | Diabetes. 2005 | 2005/03/294 years ago |
Gender-related response of lipid metabolism to dietary fatty acids in the hamster. | Morise A, Mourot J, Boué C, Combe N, Amsler G, Gripois D, Quignard-Boulangé A, Yvan-Charvet L, Fénart E, Weill P, Hermier D. | Br J Nutr. 2006 | 2006/03/314 years ago |
Long-term treatment with interleukin-1beta induces insulin resistance in murine and human adipocytes. | Lagathu C, Yvan-Charvet L, Bastard JP, Maachi M, Quignard-Boulangé A, Capeau J, Caron M. | Diabetologia. 2006 | 2006/07/264 years ago |
Prevention of adipose tissue depletion during food deprivation in angiotensin type 2 receptor-deficient mice. | Yvan-Charvet L, Even P, Lamandé N, Ferré P, Quignard-Boulangé A. | Endocrinology. 2006 | 2006/08/054 years ago |
Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow. | Ranalletta M, Wang N, Han S, Yvan-Charvet L, Welch C, Tall AR. | Arterioscler Thromb Vasc Biol. 2006 | 2006/08/194 years ago |
The failure of torcetrapib: was it the molecule or the mechanism? | Tall AR, Yvan-Charvet L, Wang N. | Arterioscler Thromb Vasc Biol. 2007 | 2007/01/194 years ago |
In vivo evidence for a role of adipose tissue SR-BI in the nutritional and hormonal regulation of adiposity and cholesterol homeostasis. | Yvan-Charvet L, Bobard A, Bossard P, Massiéra F, Rousset X, Ailhaud G, Teboul M, Ferré P, Dagher G, Quignard-Boulangé A. | Arterioscler Thromb Vasc Biol. 2007 | 2007/03/174 years ago |
Pivotal advance: macrophages become resistant to cholesterol-induced death after phagocytosis of apoptotic cells. | Cui D, Thorp E, Li Y, Wang N, Yvan-Charvet L, Tall AR, Tabas I. | J Leukoc Biol. 2007 | 2007/06/204 years ago |
High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1. | Terasaka N, Wang N, Yvan-Charvet L, Tall AR. | Proc Natl Acad Sci U S A. 2007 | 2007/09/124 years ago |
SR-BI inhibits ABCG1-stimulated net cholesterol efflux from cells to plasma HDL. | Yvan-Charvet L, Pagler TA, Wang N, Senokuchi T, Brundert M, Li H, Rinninger F, Tall AR. | J Lipid Res. 2008 | 2007/10/264 years ago |
[Raising HDL-cholesterol: the future drug therapy for atherosclerosis?]. | Masson D, Yvan-Charvet L. | Med Sci (Paris). 2008 | 2008/04/154 years ago |
Increased inflammatory gene expression in ABC transporter-deficient macrophages: free cholesterol accumulation, increased signaling via toll-like receptors, and neutrophil infiltration of atherosclerotic lesions. | Yvan-Charvet L, Welch C, Pagler TA, Ranalletta M, Lamkanfi M, Han S, Ishibashi M, Li R, Wang N, Tall AR. | Circulation. 2008 | 2008/10/154 years ago |
Role of HDL, ABCA1, and ABCG1 transporters in cholesterol efflux and immune responses. | Yvan-Charvet L, Wang N, Tall AR. | Arterioscler Thromb Vasc Biol. 2010 | 2009/10/034 years ago |
Cholesterol efflux potential and antiinflammatory properties of high-density lipoprotein after treatment with niacin or anacetrapib. | Yvan-Charvet L, Kling J, Pagler T, Li H, Hubbard B, Fisher T, Sparrow CP, Taggart AK, Tall AR. | Arterioscler Thromb Vasc Biol. 2010 | 2010/05/084 years ago |
Role of adipose tissue renin-angiotensin system in metabolic and inflammatory diseases associated with obesity. | Yvan-Charvet L, Quignard-Boulangé A. | Kidney Int. 2011 | 2010/10/154 years ago |
Cdkn2a is an atherosclerosis modifier locus that regulates monocyte/macrophage proliferation. | Kuo CL, Murphy AJ, Sayers S, Li R, Yvan-Charvet L, Davis JZ, Krishnamurthy J, Liu Y, Puig O, Sharpless NE, Tall AR, Welch CL. | Arterioscler Thromb Vasc Biol. 2011 | 2011/08/274 years ago |
ApoE regulates hematopoietic stem cell proliferation, monocytosis, and monocyte accumulation in atherosclerotic lesions in mice. | Murphy AJ, Akhtari M, Tolani S, Pagler T, Bijl N, Kuo CL, Wang M, Sanson M, Abramowicz S, Welch C, Bochem AE, Kuivenhoven JA, Yvan-Charvet L, Tall AR. | J Clin Invest. 2011 | 2011/10/054 years ago |
Cholesterol efflux and atheroprotection: advancing the concept of reverse cholesterol transport. | Rosenson RS, Brewer HB Jr, Davidson WS, Fayad ZA, Fuster V, Goldstein J, Hellerstein M, Jiang XC, Phillips MC, Rader DJ, Remaley AT, Rothblat GH, Tall AR, Yvan-Charvet L. | Circulation. 2012 | 2012/04/184 years ago |
Deficiency of ATP-binding cassette transporters A1 and G1 in macrophages increases inflammation and accelerates atherosclerosis in mice. | Westerterp M, Murphy AJ, Wang M, Pagler TA, Vengrenyuk Y, Kappus MS, Gorman DJ, Nagareddy PR, Zhu X, Abramowicz S, Parks JS, Welch C, Fisher EA, Wang N, Yvan-Charvet L, Tall AR. | Circ Res. 2013 | 2013/04/114 years ago |
Liver X receptor α-dependent iron handling in M2 macrophages: The missing link between cholesterol and intraplaque hemorrhage? | Hasty AH, Yvan-Charvet L. | Circ Res. 2013 | 2013/11/104 years ago |
ATP-binding cassette transporters, atherosclerosis, and inflammation. | Westerterp M, Bochem AE, Yvan-Charvet L, Murphy AJ, Wang N, Tall AR. | Circ Res. 2014 | 2014/01/054 years ago |
Understanding macrophage diversity at the ontogenic and transcriptomic levels. | Gautier EL, Yvan-Charvet L. | Immunol Rev. 2014 | 2014/10/174 years ago |
Cholesterol, inflammation and innate immunity. | Tall AR, Yvan-Charvet L. | Nat Rev Immunol. 2015 | 2015/01/244 years ago |
Insulin and angiotensin II induce the translocation of scavenger receptor class B, type I from intracellular sites to the plasma membrane of adipocytes. | Tondu AL, Robichon C, Yvan-Charvet L, Donne N, Le Liepvre X, Hajduch E, Ferré P, Dugail I, Dagher G. | J Biol Chem. 2005 | 2005/07/224 years ago |
ABCA1 and ABCG1 protect against oxidative stress-induced macrophage apoptosis during efferocytosis. | Yvan-Charvet L, Pagler TA, Seimon TA, Thorp E, Welch CL, Witztum JL, Tabas I, Tall AR. | Circ Res. 2010 | 2010/05/014 years ago |
Cholesterol efflux in megakaryocyte progenitors suppresses platelet production and thrombocytosis. | Murphy AJ, Bijl N, Yvan-Charvet L, Welch CB, Bhagwat N, Reheman A, Wang Y, Shaw JA, Levine RL, Ni H, Tall AR, Wang N. | Nat Med. 2013 | 2013/04/164 years ago |
HIF-2α in Resting Macrophages Tempers Mitochondrial Reactive Oxygen Species To Selectively Repress MARCO-Dependent Phagocytosis. | Dehn S, DeBerge M, Yeap XY, Yvan-Charvet L, Fang D, Eltzschig HK, Miller SD, Thorp EB. | J Immunol. 2016 | 2016/09/284 years ago |
Disruption of Glut1 in Hematopoietic Stem Cells Prevents Myelopoiesis and Enhanced Glucose Flux in Atheromatous Plaques of ApoE(-/-) Mice. | Sarrazy V, Viaud M, Westerterp M, Ivanov S, Giorgetti-Peraldi S, Guinamard R, Gautier EL, Thorp EB, De Vivo DC, Yvan-Charvet L. | Circ Res. 2016 | 2016/03/024 years ago |
Is defective cholesterol efflux an integral inflammatory component in myelopoiesis-driven cardiovascular diseases? | Yvan-Charvet L, Swirski FK. | Eur Heart J. 2018 | 2018/05/184 years ago |
The modern interleukin-1 superfamily: Divergent roles in obesity. | Lee MK, Yvan-Charvet L, Masters SL, Murphy AJ. | Semin Immunol. 2016 | 2016/10/124 years ago |
Poststatin era in atherosclerosis management: lessons from epidemiologic and genetic studies. | Yvan-Charvet L, Cariou B. | Curr Opin Lipidol. 2018 | 2018/03/204 years ago |
Inhibition of cholesteryl ester transfer protein by torcetrapib modestly increases macrophage cholesterol efflux to HDL. | Yvan-Charvet L, Matsuura F, Wang N, Bamberger MJ, Nguyen T, Rinninger F, Jiang XC, Shear CL, Tall AR. | Arterioscler Thromb Vasc Biol. 2007 | 2007/02/274 years ago |
Combined deficiency of ABCA1 and ABCG1 promotes foam cell accumulation and accelerates atherosclerosis in mice. | Yvan-Charvet L, Ranalletta M, Wang N, Han S, Terasaka N, Li R, Welch C, Tall AR. | J Clin Invest. 2007 | 2007/11/104 years ago |
ATP-binding cassette transporters G1 and G4 mediate cholesterol and desmosterol efflux to HDL and regulate sterol accumulation in the brain. | Wang N, Yvan-Charvet L, Lütjohann D, Mulder M, Vanmierlo T, Kim TW, Tall AR. | FASEB J. 2008 | 2007/11/284 years ago |
HDL, ABC transporters, and cholesterol efflux: implications for the treatment of atherosclerosis. | Tall AR, Yvan-Charvet L, Terasaka N, Pagler T, Wang N. | Cell Metab. 2008 | 2008/05/084 years ago |
ABCG1 and HDL protect against endothelial dysfunction in mice fed a high-cholesterol diet. | Terasaka N, Yu S, Yvan-Charvet L, Wang N, Mzhavia N, Langlois R, Pagler T, Li R, Welch CL, Goldberg IJ, Tall AR. | J Clin Invest. 2008 | 2008/10/184 years ago |
ATP-binding cassette transporters and HDL suppress hematopoietic stem cell proliferation. | Yvan-Charvet L, Pagler T, Gautier EL, Avagyan S, Siry RL, Han S, Welch CL, Wang N, Randolph GJ, Snoeck HW, Tall AR. | Science. 2010 | 2010/05/224 years ago |
ATP-binding cassette transporter G1 and high-density lipoprotein promote endothelial NO synthesis through a decrease in the interaction of caveolin-1 and endothelial NO synthase. | Terasaka N, Westerterp M, Koetsveld J, Fernández-Hernando C, Yvan-Charvet L, Wang N, Sessa WC, Tall AR. | Arterioscler Thromb Vasc Biol. 2010 | 2010/08/284 years ago |
[HDL and its transporters ABCA1 and ABCG1 regulate innate immunity and hematopoietic stem cell proliferation]. | Gautier EL, Yvan-Charvet L. | Med Sci (Paris). 2011 | 2011/02/094 years ago |
Anti-atherogenic mechanisms of high density lipoprotein: effects on myeloid cells. | Murphy AJ, Westerterp M, Yvan-Charvet L, Tall AR. | Biochim Biophys Acta. 2012 | 2011/08/264 years ago |
Regulation of hematopoietic stem and progenitor cell mobilization by cholesterol efflux pathways. | Westerterp M, Gourion-Arsiquaud S, Murphy AJ, Shih A, Cremers S, Levine RL, Tall AR, Yvan-Charvet L. | Cell Stem Cell. 2012 | 2012/08/074 years ago |
Cholesterol efflux: a novel regulator of myelopoiesis and atherogenesis. | Tall AR, Yvan-Charvet L, Westerterp M, Murphy AJ. | Arterioscler Thromb Vasc Biol. 2012 | 2012/10/194 years ago |
HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders. | Gautier EL, Westerterp M, Bhagwat N, Cremers S, Shih A, Abdel-Wahab O, Lütjohann D, Randolph GJ, Levine RL, Tall AR, Yvan-Charvet L. | J Exp Med. 2013 | 2013/01/164 years ago |
Mild renal dysfunction and metabolites tied to low HDL cholesterol are associated with monocytosis and atherosclerosis. | Ganda A, Magnusson M, Yvan-Charvet L, Hedblad B, Engström G, Ai D, Wang TJ, Gerszten RE, Melander O, Tall AR. | Circulation. 2013 | 2013/02/054 years ago |
Deficiency of ATP-binding cassette transporter B6 in megakaryocyte progenitors accelerates atherosclerosis in mice. | Murphy AJ, Sarrazy V, Wang N, Bijl N, Abramowicz S, Westerterp M, Welch CB, Schuetz JD, Yvan-Charvet L. | Arterioscler Thromb Vasc Biol. 2014 | 2014/02/084 years ago |
Adipose modulation of ABCG1 uncovers an intimate link between sphingomyelin and triglyceride storage. | Murphy AJ, Yvan-Charvet L. | Diabetes. 2015 | 2015/02/264 years ago |
Maintenance of Macrophage Redox Status by ChREBP Limits Inflammation and Apoptosis and Protects against Advanced Atherosclerotic Lesion Formation. | Sarrazy V, Sore S, Viaud M, Rignol G, Westerterp M, Ceppo F, Tanti JF, Guinamard R, Gautier EL, Yvan-Charvet L. | Cell Rep. 2015 | 2015/09/294 years ago |
Can LDL cholesterol be too low? Possible risks of extremely low levels. | Olsson AG, Angelin B, Assmann G, Binder CJ, Björkhem I, Cedazo-Minguez A, Cohen J, von Eckardstein A, Farinaro E, Müller-Wieland D, Parhofer KG, Parini P, Rosenson RS, Starup-Linde J, Tikkanen MJ, Yvan-Charvet L. | J Intern Med. 2017 | 2017/03/164 years ago |
Plasma metabolite profiles, cellular cholesterol efflux, and non-traditional cardiovascular risk in patients with CKD. | Ganda A, Yvan-Charvet L, Zhang Y, Lai EJ, Regunathan-Shenk R, Hussain FN, Avasare R, Chakraborty B, Febus AJ, Vernocchi L, Lantigua R, Wang Y, Shi X, Hsieh J, Murphy AJ, Wang N, Bijl N, Gordon KM, de Miguel MH, Singer JR, Hogan J, Cremers S, et al. | J Mol Cell Cardiol. 2017 | 2017/05/104 years ago |
Cholesterol Accumulation in Dendritic Cells Links the Inflammasome to Acquired Immunity. | Westerterp M, Gautier EL, Ganda A, Molusky MM, Wang W, Fotakis P, Wang N, Randolph GJ, D'Agati VD, Yvan-Charvet L, Tall AR. | Cell Metab. 2017 | 2017/05/104 years ago |
Lysosomal Cholesterol Hydrolysis Couples Efferocytosis to Anti-Inflammatory Oxysterol Production. | Viaud M, Ivanov S, Vujic N, Duta-Mare M, Aira LE, Barouillet T, Garcia E, Orange F, Dugail I, Hainault I, Stehlik C, Marchetti S, Boyer L, Guinamard R, Foufelle F, Bochem A, Hovingh KG, Thorp EB, Gautier EL, Kratky D, Dasilva-Jardine P, Yvan-Charvet L. | Circ Res. 2018 | 2018/03/114 years ago |
Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype. | Ohanna M, Cerezo M, Nottet N, Bille K, Didier R, Beranger G, Mograbi B, Rocchi S, Yvan-Charvet L, Ballotti R, Bertolotto C. | Genes Dev. 2018 | 2018/03/244 years ago |
Immunometabolism of Phagocytes and Relationships to Cardiac Repair. | Zhang S, Bories G, Lantz C, Emmons R, Becker A, Liu E, Abecassis MM, Yvan-Charvet L, Thorp EB. | Front Cardiovasc Med. 2019 | 2019/04/304 years ago |
Macrophage Origin, Metabolic Reprogramming and IL-1 Signaling: Promises and Pitfalls in Lung Cancer. | Guilbaud E, Gautier EL, Yvan-Charvet L. | Cancers (Basel). 2019 | 2019/03/064 years ago |
Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair. | Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Yvan-Charvet L, Chandel NS, Schumacker PT, Thorp EB. | Cell Metab. 2019 | 2019/01/014 years ago |
Cholesterol Mass Efflux Capacity, Incident Cardiovascular Disease, and Progression of Carotid Plaque. | Shea S, Stein JH, Jorgensen NW, McClelland RL, Tascau L, Shrager S, Heinecke JW, Yvan-Charvet L, Tall AR. | Arterioscler Thromb Vasc Biol. 2019 | 2018/12/264 years ago |
Rab4b Deficiency in T Cells Promotes Adipose Treg/Th17 Imbalance, Adipose Tissue Dysfunction, and Insulin Resistance. | Gilleron J, Bouget G, Ivanov S, Meziat C, Ceppo F, Vergoni B, Djedaini M, Soprani A, Dumas K, Jacquel A, Yvan-Charvet L, Venteclef N, Tanti JF, Cormont M. | Cell Rep. 2018 | 2018/12/204 years ago |
Immunometabolic function of cholesterol in cardiovascular disease and beyond. | Yvan-Charvet L, Bonacina F, Guinamard RR, Norata GD | Cardiovasc Res. 2019 | 2019/07/014 years ago |
Mesothelial cell CSF1 sustains peritoneal macrophage proliferation. | Ivanov S, Gallerand A, Gros M, Stunault MI, Merlin J, Vaillant N, Yvan-Charvet L, Guinamard RR. | Eur J Immunol. 2019 | 2019/114 years ago |
Granulopoiesis and Neutrophil Homeostasis: A Metabolic, Daily Balancing Act. | Yvan-Charvet L, Ng LG. | Trends Immunol. 2019 | 2019/074 years ago |
[Does sleep preserve blood vessels?]. | Yvan-Charvet L, Merlin J. | Med Sci (Paris). 2019 | 2019/10/184 years ago |
REDD1 deficiency protects against nonalcoholic hepatic steatosis induced by high-fat diet. | Dumas K, Ayachi C, Gilleron J, Lacas-Gervais S, Pastor F, Favier FB, Peraldi P, Vaillant N, Yvan-Charvet L, Bonnafous S, Patouraux S, Anty R, Tran A, Gual P, Cormont M, Tanti JF, Giorgetti-Peraldi S. | FASEB J. 2020 | 2020/044 years ago |
ABCA1 Exerts Tumor-Suppressor Function in Myeloproliferative Neoplasms. | Viaud M, Abdel-Wahab O, Gall J, Ivanov S, Guinamard R, Sore S, Merlin J, Ayrault M, Guilbaud E, Jacquel A, Auberger P, Wang N, Levine RL, Tall AR, Yvan-Charvet L. | Cell Rep. 2020 | 2020/03/104 years ago |
Interplay between Clonal Hematopoiesis of Indeterminate Potential and Metabolism. | Lee MKS, Dragoljevic D, Bertuzzo Veiga C, Wang N, Yvan-Charvet L, Murphy AJ. | Trends Endocrinol Metab. 2020 | 2020/074 years ago |
Impaired Kupffer Cell Self-Renewal Alters the Liver Response to Lipid Overload during Non-alcoholic Steatohepatitis. | Tran S, Baba I, Poupel L, Dussaud S, Moreau M, Gélineau A, Marcelin G, Magréau-Davy E, Ouhachi M, Lesnik P, Boissonnas A, Le Goff W, Clausen BE, Yvan-Charvet L, Sennlaub F, Huby T, Gautier EL. | Immunity. 2020 | 2020/09/154 years ago |
Liver X receptors are required for thymic resilience and T cell output. | Chan CT, Fenn AM, Harder NK, Mindur JE, McAlpine CS, Patel J, Valet C, Rattik S, Iwamoto Y, He S, Anzai A, Kahles F, Poller WC, Janssen H, Wong LP, Fernandez-Hernando C, Koolbergen DR, van der Laan AM, Yvan-Charvet L, Sadreyev RI, Nahrendorf M, Westerterp M, Tall AR, Gustafsson JA, Swirski FK. | J Exp Med. 2020 | 2020/10/054 years ago |
Metabolic Inflammation in Obesity-At the Crossroads between Fatty Acid and Cholesterol Metabolism. | Curley S, Gall J, Byrne R, Yvan-Charvet L, McGillicuddy FC. | Mol Nutr Food Res. 2020 | 2021/014 years ago |
Metabolic Reprogramming of Macrophages in Atherosclerosis: Is It All about Cholesterol? | Yvan-Charvet L, Ivanov S. | J Lipid Atheroscler. 2020 | 2020/054 years ago |
The OncoAge Consortium: Linking Aging and Oncology from Bench to Bedside and Back Again | Hofman P, Ayache N, Barbry P, Barlaud M, Bel A, Blancou P, Checler F, Chevillard S, Cristofari G, Demory M, Esnault V, Falandry C, Gilson E, Guérin O, Glaichenhaus N, Guigay J, Ilié M, Mari B, Marquette CH, Paquis-Flucklinger V, Prate F, Saintigny P, et al. | Cancers (Basel). 2019 | 2019/02/248 years ago |